Paracetamol

Paracetamol

The trials evaluated paracetamol and placebo usage in the short term, with the longest follow-up being 6 months so more research is needed to determine effects over a longer period of time.

Nevertheless, the authors conclude that “these results support the reconsideration of recommendations to use paracetamol for patients with low back pain and osteoarthritis of the hip or knee in clinical practice guidelines.”

In a linked editorial, Christian Mallen and Elaine Hay from Keele University write that this latest study “re-opens the debate” on the effectiveness and safety of paracetamol.

They explain that if paracetamol is taken off existing guidelines this will lead to an increase in the use other prescribed drugs, such as, opioids, and this will present new associated health problems.